Recombinant Human Anterior Gradient Protein 3 Homolog

Synonyms Anterior gradient protein 3 homolog, AG-3, AG3, hAG-3, Breast cancer membrane protein 11, AGR3, BCMP11, UNQ642/PRO1272, HAG3, PDIA18.

Introduction Anterior gradient protein 3 homolog precursor (AGR3) is a secreted cytoplasmic protein that is involved in metastasis induction and p53 tumor suppressor inhibition. AGR3 may function as molecular marker and potential therapeutic target for hormone-responsive breast tumors.

Recombinant Human Anterior Gradient Protein 3 HomologDescription AGR3 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids (22-166 a.a) and having a molecular mass of 19.5kDa.

AGR3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source Escherichia Coli. 

Physical Appearance Sterile Filtered colorless solution. 

Formulation AGR3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.

Recombinant Human Anterior Gradient Protein 3 HomologStability AGR3 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C.

Please prevent freeze thaw cycles.

Purity Greater than 90.0% as determined by SDS-PAGE. 

Amino acid sequence MGSSHHHHHH SSGLVPRGSH MGSMIAIKKE KRPPQTLSRG WGDDITWVQT YEEGLFYAQK SKKPLMVIHH LEDCQYSQAL KKVFAQNEEI QEMAQNKFIM LNLMHETTDK NLSPDGQYVP RIMFVDPSLT VRADIAGRYS NRLYTYEPRD LPLLIENMKK ALRLIQSEL.