Glutamine synthetase/GLUL/GS Antibody
Cat#：PL0301551
Isotype:Rabbit Polyclonal IgG
Immunogen：Peptide derived from human Gl Syn.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. It is found in astrocytes as an octamer of identical 42 kDa subunits. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.
Alternate Names：
Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. It is found in astrocytes as an octamer of identical 42 kDa subunits. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. The level of expression of Glutamine Synthetase is increased during ischemia in vivo or hypoxia in culture.
Specificity Reaction：Hu, Mo, Rat, Dog, Pig, Cow, Hor
Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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谷氨酰胺合成酶抗体（谷氨酸氨连接酶），Glutamine synthetase，Glutamine synthetase抗体
谷氨酰胺合成酶抗体（谷氨酸氨连接酶）
BY-0877R 谷氨酰胺合成酶抗体（谷氨酸氨连接酶）
谷氨酰胺合成酶抗体（谷氨酸氨连接酶）
人γ谷氨酸-半胱氨酸合成酶 ELISA/人γ谷氨酸-半胱氨酸合成酶 试剂盒
叔丁氧羰基-L-谷氨酸5叔丁脂/N-BOC-L-天冬氨酸叔丁酯/N-Boc-L-天冬氨酸-5-叔丁酯/叔丁氧羰基-L-谷氨酸-5-叔丁酯/Boc-L-Glutamic acid 5-benzylester
谷氨酰胺合成酶/谷氨酸氨连接酶 / 谷氨酰胺合成酶/谷氨酸氨连接酶抗体
谷氨酸半胱氨酸γ合成酶 / 谷氨酸半胱氨酸γ合成酶抗体
谷氨酸合成酶GOGAT / 谷氨酸合成酶GOGAT活性检测试剂盒
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