Pan-Cadherin Antibody
Cat#:PL0401277
Isotype:Mouse IgG1
Immunogen:peptide corresponding to the C-terminal amino acids of chicken N-Cadherin with an extra N-terminal lysine residue
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Cadherins are calcium-dependent cell-cell adhesion molecules that mediate cell-cell binding in a homophilic manner. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherin expression is regulated spatially as well as temporally. Cadherins are though to play an important role in development and maintenance of tissues through selective cell-cell adhesion activity and may be involved also in the invasion and metastasis of malignant tumors. Cadherin regulates dendritic spine morphogenesis.
Alternate Names:
UVO;CDHE;ECAD;LCAM;Arc-1;CD324;CDHN;NCAD;CD325;CDw325;CDHP;HJMD;PCAD.
Specificity Reaction:Chi, Hu, Mo, Rab, Rat
Application Notes:WB: 1:100-200 IHC: 1:200-400
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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