ITGA3 Antibody
Cat#:PL0402263
Isotype:Rabbit Polyclonal IgG
Immunogen:peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
ITGA3(INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells.
Alternate Names:
Antigen identified by monoclonal antibody J143 antibody;CD49 antigen like family member C antibody;CD49 antigen-like family member C antibody;CD49c antibody;CD49c antigen antibody;FRP2 antibody;galactoprotein B3 antibody;GAPB3 antibody.
Specificity Reaction:Hu,Mo,Rat
Application Notes:WB: 1:100-500 IHC: 1:500-1000
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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