公司销售原儿茶酸99-50-3价格中药标准品,还同时销售CP(中检所产品指定代理商)英国实验室LGC 医药杂质标准品、 加拿大TRC标准品 、EP(欧洲药典) 、USP(美国药典)、BP(英国药典) 、(WHO)世界卫生组织药物标准品 、NIST 、 美国Accustandard标准品,美国ChemService标准品等各种产品。种类齐全,到货迅速。更多详细信息欢迎您来电咨询!
产品中文名称: 原儿茶酸99-50-3价格
中文别名: 3,4-二羟基苯甲酸
英文名: 3,4-Dihydroxybenzoic acid
英文别名: Protocatechoic acid;4-Carboxy-1,2-dihydroxybenzene
CAS登录号: 99-50-3
分子式: C7H6O4
分子量: 154.03
原儿茶酸99-50-3价格分子结构:
外观: 白色至褐色结晶性粉末,在空气中变色
规格: 20mg/支
纯度: ≥ 98%
用途: 用于含量测定/鉴定/药理实验等。
提取来源: 鳞始蕨科植物乌蕨[Stenoloma chusanum(L.)Ching]的叶
溶解性: 于水、乙醇、***、丙酮,微溶于苯和***,不溶于石油醚。
熔点: 199~200℃
药理药效: 本品具有KJ作用,体外试验时对绿脓杆菌、大肠杆菌、伤寒杆菌、痢疾杆菌、产碱杆菌及枯草杆菌和金黄色葡萄球菌均有不同程度的YJ作用。亦有祛痰、平喘作用。临床用于ZL慢性气管炎。
贮存条件: 4℃冷藏、密封、避光
有效期: 2年
产品名称 | 原儿茶酸99-50-3价格
|
英文名称 | 3,4-Dihydroxybenzoic acid
|
包装 | 可根据客户要求订制 |
注意事项:格
原儿茶酸99-50-3价格纯度高,检测/鉴别精确,稳定性强,为了防止产品含量降低,不宜暴露在空气中,应防潮、避光和抗氧化包装,保存应以提高物质稳定性为原则,尽可能在干燥、低温条件下储藏(液体或易潮解物质分装在熔封的玻璃安瓶内)。
规格:规格包装齐全可根据要求定制包装。
用途:产品供科研实验使用,详情可参照产品说明书。
运输:快递免费送货上门,全国各地现货供应。
原儿茶酸99-50-3价格不能直接用于人体,出库的产品全部经过严格的检测,保证质量。标准品/对照品一般用于鉴别、检查和含量 (或效价)测定。对于鉴别来说,只要确认未混淆标准物质 即可,而检查和含量测定则不同,大部分检查项目和含量测定项目均有明确的标准。这就要求在进行检验时要控制实验误差,在进行标准物质称量时未严格按照药典等标准要求进行。
binding to the anio
nic plasma membrane phospholipid PA. This phosphorylated form localizes to the cell membrane, wher
e it is targeted by PDPK1 and PDPK2 for further phosphorylations on Thr-308 and Ser-473 leading to its activation. Ser-473 phosphorylation by mTORC2 favors Thr-308 phosphorylation by PDPK1. Ser-473 phosphorylation is enhanced by interaction with AGAP2 isoform 2 (PIKE-A). Ser-473 phosphorylation is enhanced in focal cortical dysplasias with Taylor-type balloon cells. Ser-473 phosphorylation is enhanced by signaling through activated FLT3. Dephosphorylated at Thr-308 and Ser-473 by PP2A phosphatase. The phosphorylated form of PPP2R5B is required for bridging AKT1 with PP2A phosphatase.
Ubiquitinated via 'Lys-48'-l
inked polyubiquitination by ZNRF1, leading to its degradation by the proteasome. Ubiquitinated; undergoes both 'Lys-48'- and 'Lys-63'-l
inked polyubiquitination. TRAF6-induced 'Lys-63'-l
inked AKT1 ubiquitination is critical for phosphorylation and activation. When ubiquitinated, it translocates to the plasma membrane, wher
e it becomes phosphorylated. When fully phosphorylated and translocated into the nucleus, undergoes 'Lys-48'-polyubiquitination catalyzed by TTC3, leading to its degradation by the proteasome. Also ubiquitinated by TRIM13 leading to its proteasomal degradation.
Acetylated on Lys-14 and Lys-20 by the histone acetyltransferases EP300 and KAT2B. Acetylation results in reduced phosphorylation and inhibition of activity. Deacetylated at Lys-14 and Lys-20 by SIRT1. SIRT1-mediated deacetylation relieves the inhibition.
DISEASE : Defects in AKT1 are a cause of susceptibility to breast cancer (BC) [MIM:114480]. A common malignancy originating from breast epithelial tissue. Breast neoplasms can be distinguished by their histologic pattern. Invasive ductal carcinoma is by far the most common type. Breast cancer is etiologically and genetically heterogeneous. im
portant genetic factors have been indicated by familial occurrence and bilateral involvement. Mutations at more than one locus can be involved in different families or even in the same case.
Defects in AKT1 are associated with colorectal cancer (CRC) [MIM:114500].
Note=Genetic variations in AKT1 may play a role in susceptibility to ovarian cancer.
Defects in AKT1 are a cause of Proteus syndrome (PROTEUSS) [MIM:176920]. A highly variable, severe disorder of asymmetric and disproportionate
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