产品中文名称: 去氧胆酸83-44-3售后服务
英文名: Deoxycholic acid
CAS登录号: 83-44-3
分子式: C24H40O4
分子量: 392.57
去氧胆酸83-44-3售后服务分子结构:
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外观: 白色粉末结晶
规格: 20mg/支
纯度: ≥ 98%
用途: 用于含量测定/鉴定/药理实验等。
提取来源: 为从猪胆汁中提取的一种胆烷酸 。
溶解性: 微溶于水,溶于乙醇,醚,三氧甲烷,丙酮,冰乙酸,溶于氢氧化碱和碳酸碱溶液。
熔点: 172-178℃
旋光度: +53°- +57°(c=1,乙醇)
药理药效: 解热,镇静,镇痉,XY,降压等,肝胆药物。
贮存条件: 4℃冷藏、密封、避光
有效期: 2年
去氧胆酸83-44-3售后服务标准品和对照品的本质区别:
所谓标准品,即是标准物品,作为一种衡量标准,如果用在药物方面,则为含量测定中的标准含量。标准品包括化学计量标准品、冶金标准品和药检标准品。采用生化方法来测定,目前国家规定的标准品共有15种,林可酶素、新霉素、大观酶素、太乐菌素、链霉素、卡那霉素、绒促性素、盐酶素、杆菌肽锌、安普酶素、红霉素、合成缩宫素、庆大霉素、渡毛化苷G。
所谓对照品,是指用于鉴别、检查、含量测定和校正检定仪器性能的标准物质。采用化学方法来测定,即是一般仪器的都叫做对照品,国家规定的有107种,包括地塞米松、土霉素、阿莫西林等等。
刺五加皂苷B和对照品一样是指国家药品标准中用于鉴别、检查、含量测定、杂质和有关物质检查等标准物质,它是国家药品标准不可分割的组成部分。
但刺五加皂苷B和对照品又是两个不同的概念,ZG药典凡例中有明确的定义:刺五加皂苷B是指用于生物鉴定、抗生素或生物药品中含量或效价测定的标准物质,以效价单位(U)表示,而对照品系指用于鉴别、检查、含量测定和校正检定仪器性能的标准物质。文献中经常混淆了这两个概念,认为刺五加皂苷B就是对照品,是同种物质的不同提法,之所以会有这样的误解,可能是有的药品既有刺五加皂苷B,又有对照品。例如,非那西丁当用作熔点校准物质时,用熔点刺五加皂苷B,测定含量时,用对照品;当用微生物法测定头孢克罗效价时,用头孢克罗刺五加皂苷B,用HPLC或U刺五加皂苷B法测定时,则用对照品。
去氧胆酸83-44-3售后服务特点:是一种敏感性高,特异性强,重复性好的实验诊断方法,由于其试剂稳定、易保存,操作简便,结果判断较客观等因素,已广泛应用在免疫学检验的各领域中。
检测方式:相色谱法HPLC≥98%。
贮存条件:4℃冷藏、密封、避光。
包装:可根据客户需求提供相应批量包装。
用途:用于含量测定、鉴别、药理实验、活性筛选等。
子发育相关蛋白DDX3Y抗体 规格: ?0.2ml 英文名称: DDX3Y
锌指蛋白DZIP1抗体 规格: ?0.1ml 英文名称: DZIP1
Notch信号通路Delta样配体1抗体 规格: ?0.1ml 英文名称: DLL1
DNA断裂因子抗体(蛋白酶激活脱氧核糖核酸酶) 规格: ?0.2ml 英文名称: DFFB
脱氧核糖核酸酶γ抗体 规格: ?0.2ml 英文名称: DNase gamma
死亡相关转录因子1抗体 规格: ?0.1ml 英文名称: DATF1
脱氧核糖核酸酶1抗体 规格: ?0.1ml 英文名称: DNase I
脱氧核糖核酸酶2抗体 规格: ?0.2ml 英文名称: DNase II
细胞死亡防卫蛋白1抗体 规格: ?0.2ml 英文名称: DAD1
Duffy血型趋化因子受体抗体 规格: ?0.2ml 英文名称: DARC
DEK癌基因结合蛋白 规格: ?0.1ml 英文名称: DEK
PSD95结合蛋白1抗体 规格: ?0.2ml 英文名称: DLGAP1
PSD95结合蛋白2抗体 规格: ?0.2ml 英文名称: DLGAP2
PSD95结合蛋白4抗体 规格: ?0.2ml 英文名称: DLGAP4
cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons.
Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid 42 is a more effective reductant than beta-amyloid 40. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalyzed oxidation of lipoproteins. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses. Promotes both tau aggregation and TPK II-mediated phosphorylation. Interaction with overexpressed HADH2 leads to oxidative stress and neurotoxicity.
Appicans elicit adhesion of neural cells to the extracellular matrix and may regulate neurite outgrowth in the brai.
The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
去氧胆酸83-44-3售后服务N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
Subunit : Binds, via its C-terminus, to the PID domain of several cytoplasmic proteins, including APBB family members, the APBA family, MAPK8IP1, SHC1 and, NUMB and DAB. Binding to DAB1 inhibits its serine phosphorylation (By similarity). Also