4-14-4 15-Keto Prostaglandin E0 2800TRC K200827 / 1mgrac Ketoprofen Amide-13C,d3 2800TRC K200815 / 1mg 140148-25-0 (R)-Ketoprofen Acyl-β-D-glucuronide 2800TRC K186500 / 5mg 1415558-82-5 2-Keto Crizotinib 2800TRC K186010 / 2.5mg 83374-59-8 rac-trans-Ketoconazole 2800TRC J211422 / 1mgJWH-175-d11 2800TRC J211335 / 1mg 259869-55-1 JW 133 (10 mg/mL in Methyl Acetate) 2800TRC J211250 / 1mg 16298-90-1Discontinued 2800TRC J210522 / 1mg 903510-51-0 rac-trans Jasmonic Acid 2800TRC I931004 / 0.5mgItaconic Acid-13C5 2800TRC I902102 / 1mg 1217604-00-6 Isosorbide-13C6 5-Mononitrate, 90% 2800TRC I900802 / 1mgIso Sildenafil-d3 2800TRC I872750 / 100mg 3736-31-0 N-Isopropylnoradrenochrome 2800TRC I872275 / 5mg9-Isopropyl-2-methylbenz[a]anthracene 2800TRC I822820 / 250mg 14559-87-6 Isopropenylboronic Acid 2800TRC I821970 / 5mg 531-35-1 Isopilocarpine 2800TRC I820877 / 1mgIsolopinavir-d9 2800TRC I816602 / 1mgIsoflupredone-d3 (d2 Major) 2800TRCsmall GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013].
Function : Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle 土霉素麦芽提取物琼脂培养基价格microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.
Subunit : The GTP-bound form interacts with
土霉素麦芽提取物琼脂培养基价格培养和保存:
1)干粉,买了后一定要保存在4度。有人保存在-20度我认为没有必要。但4度是非常必要的。保证期是有提示的。
2)配好的无血清培养基一定保存在4度,保存不要超过3个月。用时根据提示要加入谷胺酰胺。
3)加入血清的培养基,保存在4度不要超过1个月,从时间太长,活性下降。当然稍微长点也不一定出问题。但是根据细胞而定;如果原代培养,新鲜,如果是肿瘤细胞,或仅维持传代就不太要紧。但是原则是越新越好。