背景介绍:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
别名:hR PTPu; Protein tyrosine phosphatase mu; Protein tyrosine phosphatase receptor type M; Protein tyrosine phosphatase receptor type mu polypeptide; Protein-tyrosine phosphatase mu; PTPRL1; Ptprm; PTPRM_HUMAN; R PTP mu; R-PTP-mu; Receptor type tyrosine protein phosphatase mu; Receptor-type tyrosine-protein phosphatase mu; RPTPM; RPTPU.
蛋白酪氨酸磷酸酶亩mu抗体,Anti-PTP mu抗体简单介绍:
产品编号:BYK-18838R
英文名称:Anti-PTP mu
中文名称:蛋白酪氨酸磷酸酶亩mu抗体
产品规格:50ul;100ul;200ul;1ml,品质保证
抗体来源 Rabbit or Mouse
克隆类型 Polyclonal or Monoclonal
交叉反应、产品应用 (具体交叉反应与产品应用请或添加客服直接索取)
性 状 Lyophilized or Liquid
浓 度 1mg/ml
蛋白酪氨酸磷酸酶亩mu抗体,Anti-PTP mu抗体产品信息:
博研生物小课堂:
常用激光器对应荧光素的选择:
蓝色激光器荧光素(488nm):Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7
红色激光器荧光素(633nm):APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647
黄色激光器荧光素(561nm):PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594
流式抗体选择标准
确定流式细胞仪的参数配置
在设计流式方案前,先确定需要使用流式细胞仪检测的型号,对该仪器的参数配置要了解以下几个方面信息:
激光器:常见的流式细胞仪有488nm和635nm/633nm两个激光器,但有些机器在购买时因某些原因,只装了一个488nm激光器,所以需要注意型号相同的机器也未必激光配置相同。
滤光片:也就是有几个检测通道,这决定了你zui多可以同时检测几个指标。
仪器的具体型号:有助于再次确定检测通道。因为同一个荧光在不同的流式细胞仪上检测,有时候检测通道也是不一样的。
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