背景介绍:This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D); a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
别名:Melanin concentrating hormone;PMCH; MCH_HUMAN; Pro MCH; Pro melanin concentrating hormone.
黑色素聚集激素抗体,Anti-PMCH抗体简单介绍:
产品编号:BYK-18725R
英文名称:Anti-PMCH
中文名称:黑色素聚集激素抗体
产品规格:50ul;100ul;200ul;1ml,品质保证
抗体来源 Rabbit or Mouse
克隆类型 Polyclonal or Monoclonal
交叉反应、产品应用 (具体交叉反应与产品应用请或添加客服直接索取)
性 状 Lyophilized or Liquid
浓 度 1mg/ml
黑色素聚集激素抗体,Anti-PMCH抗体产品信息:
免疫荧光染色与免疫组化前期处理相同,因为内源性过氧化物酶对免疫荧光实验没有影响,同时双氧水反而会干扰到荧光素发光,所以这步操作在免疫荧光中不需要做。
常用的荧光显微镜一般有三个通路,激发波长为350nm、488nm、555nm附近,分别对应的荧光发射光颜色为蓝光、绿光、红光。
350nm常用荧光素:DAPI(复染用),Alexa Fluor 350
488nm常用荧光素:FITC,Alexa Fluor 488
555nm常用荧光素:PE、Cy3、Rhodamine B、Alexa Fluor555
另有其他常见荧光素
594nm常用荧光素:Texas Red、Alexa Fluor594
647nm常用荧光素:Cy5、APC、Alexa Fluor647
黑色素聚集激素抗体,Anti-PMCH抗体相关产品:
Anti-RXR Alpha/RXRA/Retinoid X receptor 核受体RXRα抗体
Anti-RRAD RRAD抗体
Anti-phospho-PIK3 gamma(Thr1024) 磷酸化磷脂酰肌醇激酶PIK3-γ抗体
Anti-phospho-Rb/p105-Rb(Ser780) 磷酸化成视网膜细胞瘤抑癌蛋白抗体
Anti-GRID2IP 谷氨酸受体δ2/GluR-δ2抗体
Anti-ROS/c ros 活性氧簇ROS抗体
Anti-AOA1/Aprataxin 共济失调性眼球运动功能丧失相关蛋白AOA1抗体
Anti-RPLP0 酸性核糖体磷蛋白大亚基P0抗体
Anti-METRN Meteorin神经胶质细胞分化调节蛋白抗体
Anti-ROCK2 Rho相关蛋白激酶2抗体
Anti-SorLA/LRP9 低密度脂蛋白受体相关蛋白9抗体
Anti-ROCK1 Rho相关蛋白激酶1抗体
Anti-RNF148 环指蛋白148抗体
Anti-Calcyphosine 2/CAPS2 钙磷蛋白2抗体