CD74抗体，Anti-CD74/MHC II抗体

“CD74抗体，Anti-CD74/MHC II抗体”应用于IHC、WB、 IF、IP、ELISA，质量保证，无效免费退换，另外本公司生产经营各种标记二抗、免疫印迹常用试剂、免疫组化常用试剂，咨询！

产品介绍：

【产品名称】：CD74抗体，Anti-CD74/MHC II抗体

【产品类型】：一抗

【产品编号】：BYk-2518R                    

【相关标记】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647

【性 状】： Lyophilized or Liquid

【浓 度】： 1mg/1ml

【亚 型】： IgG

【规 格】：0.1ml/100ug，0.2ml/200ug

【抗体来源】： Rabbit OR MOUSE

【克隆类型】： polyclonal or monoclonal

【产品用途】：科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。

【贮 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

【详细介绍】：CD74, also known as the MHC class II associated invariant chain （Ii）, is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is produced in molar excess over MHC class II and some of this is expressed by an unknown pathway on the cell surface independent of, or in association with, MHC class II molecules. The half life of CD74 on the cell surface is only 3 to 4 min after which it is internalized. It has been proposed that cell surface CD74 binds MHC class II molecules which have lost their antigenic peptide leading to internalization and reloading with antigenic peptide. The transport route of class II alpha/beta/Ii complexes is regulated selectively by two forms of CD74 （p33 and p35） which are generated by the use of alternative translation initiation sites.
CD74 is expressed primarily by antigen presenting cells such as B lymphocytes （from before the pre-B cell stage to before the plasma cell stage）, macrophages and monocytes together, with many epithelial cells. CD74 may exist in different isoforms ranging in size from 33 to 41 kDa, depending on genetic splicing.
CD74抗体，Anti-CD74/MHC II抗体【相关产品】：
Anti-IL-4  白介素4抗体（大、小鼠）
Anti-IL-4  白介素4抗体（人）
Anti-IL-4R  白细胞介素4受体抗体
Anti-IL-5  白介素5抗体
Anti-IL-5Rα/CD125  白介素-5受体α链抗体
Anti-IL-6 Human  白介素6（人）
Anti-IL-6   白介素6抗体（大、小鼠）
Anti-IL-6   mouse rat  白介素6抗体
Anti-IL-7  白介素7抗体
Anti-IL-6Rα   白细胞介素6受体α抗体
Anti-IL6Rβ/CD130/gp130  白细胞介素6受体β抗体
Anti-IL-8/CXCL8  白介素8抗体
Anti-IL-8/CXCL8  白介素8抗体（大、小鼠）
Anti-IL-7Ra/CD127  白细胞介素-7受体a抗体
Anti-Mitofilin/IMMT  线粒体内膜蛋白抗体
Anti-ILK-1   整合素连接激酶-1抗体
Anti-ILTV  抗鸡传染性喉气管炎病毒抗体
Anti-ING1/p33  生长YZ因子基因1抗体
Anti-IMP3  胰岛素样生长因子ⅡmRNA结合蛋白3抗体
Anti-Inhibin α  YZ素α抗体
Anti-Inhibin beta A  YZ素beta A抗体
Anti-Inhibin beta B  YZ素βB抗体
Anti-Inhibin β C/Inhibin beta C  YZ素βC抗体
Anti-Insulin  胰岛素抗体
Anti-Insulin Receptor-α  胰岛素受体-α抗体