规格: | 0.5mg | 产品价格: | 5250.00 |
---|
规格: | 1mg | 产品价格: | 9450.00 |
---|
Catalog Number H-5088
Synonyms (Gly¹,Gln⁴·¹⁶,Thr⁶·¹³,Tyr⁷,Asp¹⁰,Asn¹¹,Pro¹⁴,Arg²⁶,Met³⁰,Ala³¹,Aib³²)-Neuropeptide Y (human, rat)
Molecular Formula C₁₈₃H₂₈₁N₅₇O₅₄S₂
Relative Molecular Mass 4207.73
CAS Registry Number [313988-89-5] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Obesity Research
产品描述
This (Ala-Aib)-containing pancreatic peptide/neuropeptide Y chimera is a highly selective neuropeptide Y₅ receptor agonist. At this receptor this compound turned out to be 25-fold more potent than the derivative H-5084 (0.24 nM vs 6 nM) and three-fold more potent than the native ligand neuropeptide Y (H-6375) (0.24 nM vs 0.6 nM). This analog turned out to increase feeding approximately 2.5-fold more effective than neuropeptide Y.
论文引用
• A.Santos-Carvalho et al., Cell Death Dis., 4, e636 (2013)
• S.Baptista et al., Neuropharmacology, 62, 2413 (2012)
• A.P.Silva et al., J. Neurochem., 93, 163 (2005)
更多产品信息,请点击:https://shop.bachem.com/4035069.html原装进口,(Gly¹,Ser³·²²,Gln⁴·³⁴,Thr⁶,Arg¹⁹,Tyr²¹,Ala²³·³¹,Aib³²)-Pancreatic Polypeptide (human) trifluoroacetate salt,bachem品Pai大包装更优惠!
瑞士巴亨公司(Bachem)是世界上合成多肽产品ZD的生产企业。Bachem公司免疫学产品,覆盖多种标记的树突细胞、内皮细胞、巨噬细胞、单核细胞抗体及各种Elisa检测试剂盒。酶免疫测定试剂盒具有高敏感度、高特异性及无放射性的特点,使用更有效操作更简单!可广泛应用于细胞凋亡、肿瘤、心血管和高血压疾病、糖尿病、肥胖症及肠胃道疾病、脑垂体和下丘脑激素及神经科学的研究。
![](http://item.yiqi.com/pic/ConPic/4/C1527582775145hz3bpc82expng_small.jpg)
![](http://item.yiqi.com/pic/ConPic/4/C1527586819137su6ntx3fcn_small.jpg)
温馨提示:不可用于临床ZL。