(d(CH₂)₅¹,Tyr(Me)²,Orn⁸)-Oxytocin trifluoroacetate salt

产品描述
Potent oxytocin antagonist with a pA₂ value of 7.35 ± 0.08. (d(CH₂)₅¹,Tyr(Me)²,Orn⁸)-Vasotocin has been used to support the hypothesis that pituitary secretion of oxytocin is associated with coactivation of centrally projecting brain oxytocin pathways, some of which are causally related to the induced inhibition of food intake. Furthermore, this compound competitively inhibited arginine vasotocin (AVT) contractions without affecting AVT efficacy.

论文引用
• Z.Y.Ong et al., Am. J. Physiol. Regul. Integr. Comp. Physiol., 308, R800 (2015)
• J.M.Ho et al., Endocrinology, 155, 2845 (2014)
• K.Mullis et al., Brain Res., 1513, 85 (2013)
• F.Sanna et al., Pharmacol. Biochem. Behav., 103, 750 (2013)
• H.S.Knobloch et al., Neuron, 73, 553 (2012)
• T.M.D'Cunha et al., Horm. Behav., 59, 14 (2011)
• H.Iwakura et al., Endocrinology, 152, 2619 (2011)
• R.Babygirija et al., Am. J. Physiol. Regul. Integr. Comp. Physiol., 298, r157 (2010)
• D.G.Baskin et al., Endocrinology, 151, 4207 (2010)
• Y.Maejima et al., Cell Metab., 10, 355 (2009)
• P.Clement et al., Br. J. Pharmacol., 154, 1150 (2008)
• B.M.Kublaoui et al., Mol. Endocrinol., 22, 1723 (2008)
• K.L.Bales et al., Neuroscience, 144, 38 (2007)
• K.M.Kramer et al., BMC Neurosci., 8, 71 (2007)
• S.Succu et al., Neuropharmacology, 52, 1034 (2007)
• Y.Yamamoto et al., Neuroscience, 137, 157 (2006)
• S.Filippi et al., Endocrinology, 146, 3506 (2005)
• S.Succu et al., Neuropharmacology, 49, 1017 (2005)
• L.Vignozzi et al., Endocrinology, 145, 1823 (2004)
• S.Filippi et al., Endocrinology, 143, 4271 (2002)
• Z.Yang et al., Exp. Physiol., 87, 663 (2002)

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