规格: | 0.5mg | 产品价格: | 3750.00 |
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规格: | 1mg | 产品价格: | 6750.00 |
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Catalog Number H-4592
Synonyms (Ser⁸)-Glucagon-Like Peptide 1 (7-36) amide (human, bovine, guinea pig, mouse, rat), (Ser⁷⁹)-Proglucagon (78-107) amide (human, bovine, guinea pig, mouse, rat), (Ser⁹⁹)-Preproglucagon (98-127) amide (human, bovine, guinea pig, mouse, rat)
Molecular Formula C₁₄₉H₂₂₆N₄₀O₄₆
Relative Molecular Mass 3313.68
CAS Registry Number [215777-46-1] net
One Letter Code HSEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH₂
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Diabetes
产品描述
The replacement of alanine by serine significantly improved the plasma stability of GLP-1 (7-36) amide against DPP IV without impairing its insulinotropic activity. This may indicate that this modification could improve the potential of GLP-1 in the treatment of type-II diabetes.
论文引用
• T.Shigemori et al., AMB Express, 5, 26 (2015)
• A.Maida et al., Gastroenterology, 137, 2146 (2009)
• A.J.Kastin et al., J. Mol. Neurosci., 18, 7 (2002)
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温馨提示:不可用于临床ZL。