H-His-Cys-Lys-Phe-Trp-Trp-OH

产品描述
HCKFWW, potent inhibitor of the HIV-encoded integrase (IN), the enzyme responsible for the integration of HIV DNA into the human genome. HCKFWW inhibits IN-mediated 3'processing and integration with an IC₅₀ of 2 µM. The peptide is also active on IN proteins from other retroviruses such as HIV-2, feline immunodeficiency virus and Moloney murine leukemia virus. It was also found to inhibit the disintegration reaction, suggesting that this hexapeptide acts at or near the catalytic site of IN.

酶
HIV Integrase:YZ剂

论文引用
• J.R.Aponte et al., Anal. Chem., 86, 6237 (2014)
• L.Vasicek and J.S.Brodbelt, Anal. Chem., 81, 7876 (2009)
• D.Ren et al., Anal. Chem., 76, 4522 (2004)

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瑞士巴亨公司（Bachem）是世界上合成多肽产品ZD的生产企业。Bachem公司免疫学产品，覆盖多种标记的树突细胞、内皮细胞、巨噬细胞、单核细胞抗体及各种Elisa检测试剂盒。酶免疫测定试剂盒具有高敏感度、高特异性及无放射性的特点，使用更有效操作更简单！可广泛应用于细胞凋亡、肿瘤、心血管和高血压疾病、糖尿病、肥胖症及肠胃道疾病、脑垂体和下丘脑激素及神经科学的研究。

温馨提示：不可用于临床ZL。