规格: | 0.5mg | 产品价格: | 6900.00 |
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规格: | 1mg | 产品价格: | 11550.00 |
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Catalog Number H-2932
Synonyms ADM (1-52) (human), Adrenomedullin (1-52), human
Molecular Formula C₂₆₄H₄₀₆N₈₀O₇₇S₃
Relative Molecular Mass 6028.82
CAS Registry Number [148498-78-6] net
One Letter Code YRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH₂
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Apoptosis & Necrosis|Cardiovascular System & Diseases
产品描述
Adrenomedullin (ADM) elicits a potent and longlasting hypotensive effect and is considered as a hormone involved in blood pressure control. Additionally, ADM acts as a protective factor of blood vessels.
Adrenomedullin is a potent stimulator of osteoblastic activity. Further biological activities of hADM include reduction of oxidative stress and inhibition of endothelial cell apoptosis.
论文引用
• M.J.Woolley et al., Biochem. Pharmacol., (2017)
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• E.Liverani et al., Int. Immunopharmacol., 14, 75 (2012)
• E.Talero et al., Mediators Inflamm., 2012, 717851 (2012)
• M.D.Ah Kioon et al., Arthritis Res. Ther., 12, R190 (2010)
• S.M.Kim et al., FEBS Lett., 584, 213 (2010)
• A.P.Fontes-Sousa et al., Peptides, 30, 796 (2009)
• J.Simms et al., Biochemistry, 48, 198 (2009)
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• L.Juhl et al., Eur. J. Pharmacol., 538, 101 (2006)
• P.Hasbak et al., Br. J. Pharmacol., 145, 646 (2005)
• I.Abasolo et al., Biochem. Biophys. Res. Commun., 322, 878 (2004)
• E.S.Dettmann et al., Invest. Ophthalmol. Vis. Sci., 44, 3961 (2003)
• D.L.Hay et al., Br. J. Pharmacol., 140, 477 (2003)
• J.J.Miret et al., J. Biol. Chem., 277, 6881 (2002)
• L.Ouafik et al., Am. J. Pathol., 160, 1279 (2002)
• A.Sams et al., Eur. J. Pharmacol., 408, 183 (2000)
• N.Aiyar et al., Mol. Cell. Biochem., 197, 179 (1999)
更多产品信息,请点击:https://shop.bachem.com/4030315.html原装进口,Adrenomedullin (human) trifluoroacetate salt,bachem品Pai大包装更优惠!
瑞士巴亨公司(Bachem)是世界上合成多肽产品ZD的生产企业。Bachem公司免疫学产品,覆盖多种标记的树突细胞、内皮细胞、巨噬细胞、单核细胞抗体及各种Elisa检测试剂盒。酶免疫测定试剂盒具有高敏感度、高特异性及无放射性的特点,使用更有效操作更简单!可广泛应用于细胞凋亡、肿瘤、心血管和高血压疾病、糖尿病、肥胖症及肠胃道疾病、脑垂体和下丘脑激素及神经科学的研究。
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