Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)

产品描述
Ac-DEVD-CHO is a potent inhibitor of the poly(ADP-ribose) polymerase (PARP) cleavage by caspase-3 (IC₅₀ = 0.2 nM). PARP cleavage occurs at the onset of apoptosis. The peptide aldehyde was able to attenuate apoptotic events in vitro (IC₅₀ = 10 to 100 nM).

酶
Caspase-3 (CPP-32; Yama; Apopain):YZ剂|Caspase-6 (Mch2):YZ剂|Caspase-8 (MACH; FLICE; Mch5):YZ剂|Caspase-9 (ICE-LAP6; Mch6):YZ剂|Caspase-10:YZ剂|Caspase-1 (ICE):YZ剂|Caspase-7 (ICE-LAP3; Mch3; CMH-1):YZ剂

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