N-Trifluoroacetyl-N-methyl-deacetylcolchiceine

1) 【订购咨询热线400-811-9081 13681619662 】 货号：T789500; （2）化学名 N-Trifluoroacetyl-N-methyl-deacetylcolchiceine; 3) CAS No.: 1217782-80-3; 4) 分子式: C22H22F3NO6; 5)分子量 453.41; 6) 包装 100mg / 1g; 7)性状: Yellow Solid; 8) 应用领域 An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.; 9) 别称: 2,2,2-Trifluoro-N-methyl-N-[(7S)-5,6,7,9-tetrahydro-10-hydroxy-1,2,3-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide;; 10)溶解性: Chloromethane, Dichlormethane, DMSO, Methanol; 11)储存条件: ; 12)参考文献 Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),