SB203580|SB-203580 is an inhibitor of p38 MAPK that exhibits immunostimulatory, anticancer, and anti-fibrotic activities. In peripheral blood mononuclear cells, SB-203580 increases secretion of IFN- . In lung epithelial cells, SB-203580 inhibits TGB- 1-induced epithelial-to-mesenchymal transition (EMT). Additionally, SB-203580 inhibits proliferation in glioma cells and decreases angiotensin II- and TGB- 1-induced expression of GTGF and fibronectin in other cellular models.|C21H16FN3OS|377.43||-20°C|
温馨提示:不可用于临床ZL。