|Rivastigmine is an inhibitor of acetylcholinesterase (AChE) and butylcholinesterase (BChE) that is used clinically to treat dementia. Rivastigmine exhibits anti-cholinergic, anti-inflammatory, cognition enhancing and neuroprotective activities. In vivo, rivastigmine improves memory impairment in a CaMKII-dependent manner. Rivastigmine also decreases production of IL-1 in vivo. In vitro, this compound displays benefit against Alzheimer’s disease, increasing secretion of amyloid- (A ) precursor protein (APP) and decreasing secretion of A through modulation of -secretase signaling.|C18H28N2O8|400.42||Ambient|
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