β-Endorphin, rat |CAS:|1 mg|2 mg|5 mg

| -Endorphin is an endogenous opioid peptide that acts as an agonist at -opioid receptors ( ORs) and exhibits immunomodulatory, neuromodulatory, antidepressant, and antinociceptive/analgesic activities. In vivo, -endorphin increases levels of B-cells and production of antibodies as well as secretion of IL-4 and proliferation of spleenocytes, shifting the immune response toward Th2-specific mediators. This peptide, like other endogenous opioids, plays a significant role in reward and reinforcement signaling, especially in brain regions such as the ventral tegmental area (VTA) and nucleus accumbens (NAcc). -Endorphin release is induced during exercise and shows antidepressant activity in clinical studies.|C157H254N42O44S|3466.09||+4°C|