AD-810; CI-912; Excegran|Zonisamide is a sulfonamide that exhibits antiepileptic/anticonvulsant and neuroprotective activity and is clinically used to prevent seizures and epilepsy. Zonisamide inhibits carbonic anhydrase, voltage-gated Na+ channels, T-type Ca2+ channels, and release of GABA and glutamate. In animal models of Parkinson’s disease, zonisamide delays neurodegeneration.|C8H8N2O3S|212.23||Ambient|Sparingly soluble in water. Soluble in methanol, ethanol, DMSO.
温馨提示:不可用于临床ZL。