3-Aminobenzamide ≥97%|CAS:3544-24-9|100 mg|250 mg|500 mg

3-AB; 3-ABA, INO-1001|3-Aminobenzamine is an inhibitor of poly(ADP)-ribosyl polymerase (PARP) that exhibits cytoprotective, anti-atherosclerotic, and anticancer activities. 3-Aminobenzamide prevents UV-induced cell death in vitro and inhibits TGF- 1-induced phosphorylation of Smad3 in other cellular models. In vivo, this compound inhibits production of inflammatory cytokines, suppresses PARP activation, and decreases atherosclerotic lesion size. Additionally, 3-aminobenzamide induces G1 phase cell cycle arrest, downregulates expression of cyclin D1, -catenin, c0Jun, c-Myc, and Id2, upregulates expression of p21 and genes involved in differentiation, and induces differentiation in osteosarcoma cells.|C7H8N2O|136.15||+4°C|Soluble in DMSO or ethanol.