Hebanil; Klorpromex; Largactil; Megaphen; Promacid; Chloractil; Sonazine; Marazine; Taroctyl; Torazina|Chlorpromazine is a phenothiazine that exhibits anti-psychotic, antidepressant, anxiolytic, neuroprotective, and anticancer chemotherapeutic activities. Chlorpromazine inhibits D1/2/3/4 receptors, 5-HT1/2 receptors, 1/2-adrenergic receptors, and M1/2 muscarinic acetylcholine receptors (mAChRs). Chlorpromazine stabilizes misfolding motifs of prions, preventing oligomerization. Additionally, this compound acts as a functional inhibitor of acid sphingomyelinase (FIASMA). In vivo, chlorpromazine induces autophagy and apoptosis, inhibiting growth of glioma tumors.|C17H19Cl2N2S HCl|355.3|Off-White powder|Ambient|Soluble in methanol, ethanol (660 mg/mL), chloroform or water (1 g/mL). Insoluble in ether, or benzene.
温馨提示:不可用于临床ZL。