Nimesulide ≥98%|CAS:51803-78-2|1 g|5 g|10 g

Aulin; Fansidol; Flogovital; Mesulid; Nide; Nidol; Nisulid|Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Nimesulide exhibits anti-inflammatory, analgesic, antipyretic, and anticancer activities. Nimesulide is clinically used to treat arthritis, acute pain, and dysmenorrhea. In hypopharyngeal carcinoma cells, nimesulide decreases cell viability, increases apoptosis, downregulates expression of survivin, COX-2, and Bcl-2, and upregulates expression of caspase 3 and Bax. In vitro under inflammatory conditions, this compound decreases activity of PKC and release of substance P and prostaglandin E2 (PGE2).|C13H12N2O5S|308.31||Ambient|Soluble in chloroform.