Alpha-2-glycoprotein / AZGP1抗体

Alpha-2-glycoprotein / AZGP1抗体产品信息

免疫原 :    
Recombinant Human Alpha-2-glycoprotein / AZGP1 protein (Catalog#13242-H08H)
Antibody Type :    Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :    
Rabbit IgG
缓冲液 :    0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :    
Produced in rabbits immunized with purified, recombinant Human Alpha-2-glycoprotein / AZGP1 (rh Alpha-2-glycoprotein / AZGP1; Catalog#13242-H08H; P25311; Met1-Ser298). Total IgG was purified by Protein A affinity chromatography.
Alpha-2-glycoprotein / AZGP1抗体Background
Alpha-2-glycoprotein, also known as AZGP1, is a member of the MHC class I family. It has been identified as a novel adipokine since it is produced by both white and brown fat adipocytes and may act in a local autocrine fashion in the reduction of adiposity in cachexia. Alpha-2-glycoprotein can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can stimulate lipolysis by adipocytes in vivo and in vitro. Thus it is believed that alpha-2-glycoprotein plays an important role in the regulation of body weight, and age-dependent changes in genetically influenced obesity, and it also regulates melanin production by normal and malignant melanocytes. Alpha-2-glycoprotein may bind polyunsaturated fatty acids. It can cause the extensive fat loss associated with some advanced cancer.
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