Biotin anti-mouse CD1d (CD1.1, Ly-38)_详细资料

产品信息

克隆性：多克隆保存条件：蓝冰规格： 500 ug

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Biotin anti-mouse CD1d (CD1.1, Ly-38)参数介绍>>>>

Clone 1B1
Isotype Rat IgG2b, κ
Reactivity Mouse
Immunogen Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Concentration 0.5mg/ml
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Applications
FC - Quality tested
IHC - Reported in the literature
Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation, immunohistochemistical staining, and blocking function³.

This product is for research use only and is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic, therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes, contact the Regents of the University of California.
Application References
1. Fischer K, et al. 2004. P. Natl. Acad. Sci. USA 101:10685. (Block)
2. Brozovic S, et al. 2004. Nat. Med. 10:535.
3. Brossay L, et al. 1997. J. Immunol.. 159:1216. (Block)
Description
CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e). But CD1d is the only CD1 molecule has been found in mouse. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. It has been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.
Storage The antibody solution should be stored undiluted at 4°C. Do not freeze.

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Clone	1B1
Isotype	Rat IgG2b, κ
Reactivity	Mouse
Immunogen	Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma
Formulation	Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation	The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Concentration	0.5mg/ml
Recommended Usage	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Applications	FC - Quality tested IHC - Reported in the literature
Application Notes	Additional reported applications (for the relevant formats) include: immunoprecipitation, immunohistochemistical staining, and blocking function³. This product is for research use only and is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic, therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes, contact the Regents of the University of California.
Application References	1. Fischer K, et al. 2004. P. Natl. Acad. Sci. USA 101:10685. (Block) 2. Brozovic S, et al. 2004. Nat. Med. 10:535. 3. Brossay L, et al. 1997. J. Immunol.. 159:1216. (Block)
Description	CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e). But CD1d is the only CD1 molecule has been found in mouse. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. It has been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.
Storage	The antibody solution should be stored undiluted at 4°C. Do not freeze.