Recombinant Human β-NGF
产品编号:
450-01
别名:
NGF-β
描述:
β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers (240 total amino acid residues). The three disulfide bonds are required for biological activity.
氨基酸序列:
SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
determined by its ability to stimulate chick E9 DRG neurite outgrowth. The ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
交叉反应:
Chicken, Hamster, Mouse, Rat
研究领域:
| 血管生成/ 心血管 | | 趋化 |
| 糖尿病/ 体重调节 | | 炎症 |
| 神经生物学 | | 干细胞及分化 |
| 创伤修复 | | |
原产国:
USA
产品包装:
相关产品
检测产品
- Human β-NGF ELISA Development Kit
- Human β-NGF Mini ELISA Development Kit
抗体
- Anti-Human β-NGF
- Anti-Human β-NGF (Monoclonal Antibody)
- Biotinylated Anti-Human β-NGF
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