ω-Conotoxin MVIIC / Omega conotoxin MVIIC _详细资料

产品信息

Smartox Biotechnology是WY一家专门生产动物毒液多肽毒素，用于细胞离子通道功能研究的生物医药公司。多肽毒素在生物制药领域具有重要的使用价值。

Catalog N : 08CON002ω-Conotoxin MVIIC / Omega conotoxin MVIIC
Blocker of P/Q and N-type Ca²⁺ channels

ω-conotoxin MVIIC (omega conotoxin MVIIC) has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q and N-type calcium channels. It inhibits presynaptic Ca²⁺ channels, including the Ca²⁺ channels responsible for Ca²⁺ uptake by rat brain synaptosomes, the P-type Ca²⁺ channels in cerebellar Purkinje cells, and a significant fraction of ω-conotoxin GVIA-resistant currents in hippocampal CA1 neurons. ω-conotoxin MVIIC also presents an inhibition of ω-conotoxin GVIA-resistant depolarization-induced neurotransmitter release in cerebellar neurons of rats.

ω-conotoxin MVIIC technical information
AA sequence: Cys¹-Lys-Gly-Lys-Gly-Ala-Pro-Cys⁸-Arg-Lys-Thr-Met-Tyr-Asp-Cys¹⁵-Cys¹⁶-Ser-Gly-Ser-Cys²⁰-Gly-Arg-Arg-Gly-Lys-Cys²⁶-NH₂
Disulfide bonds: Cys¹-Cys¹⁶, Cys⁸-Cys²⁰ and Cys¹⁵-Cys²⁶
Length (aa): 26
Formula: C₁₀₆H₁₇₈N₄₀O₃₂S₇
Molecular Weight: 2750.20 Da
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number: [147794-23-8]
Source: Synthetic
Purity rate: > 97 %

08CON002-00100 ω-conotoxin MVIIC 0.1mg

08CON002-00500 ω-conotoxin MVIIC 0.5mg

08CON002-01000 ω-conotoxin MVIIC 1mg

温馨提示：不可用于临床ZL。

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08CON002-00100	ω-conotoxin MVIIC	0.1mg
08CON002-00500	ω-conotoxin MVIIC	0.5mg
08CON002-01000	ω-conotoxin MVIIC	1mg