Nav 1.7 Inhibitor, Ssm6a

Synthetic. Supplied as a TFA salt. A unique 46-resiude peptide originally isolated from the venom of Chinese red-headed centipede. Ssm6a potently inhibits sodium channel NaV1.7 with an IC₅₀ of ∼25 nM. µ-SLPTX-Ssm6a has more than 150-fold selectivity for NaV1.7 over all other human NaV subtypes, with the exception of NaV1.2, for which the selectivity is 32-fold. Displays more analgesic properties than morphine in rodent pain models.