Von Frey纤毛机械刺激针(Von Frey hairs test Von Frey Filaments, Semmes-Weinstein monofilament 含20根Von Frey尼龙纤维丝,它可提供0.008g-300g的刺激力可对多种动物进行定量的痛觉测试,主要用于von Frey hairs test评估皮肤的机械痛阈或触觉阈测量。
Von Frey hairs纤毛机械刺激针的粗细及伸出长度决定提供刺激力的大小。实验时,根据实际情况选定粗细当得的Von Frey hairs纤毛机械刺激针,调节适当Von Frey hairs纤毛机械刺激针的伸出长度,垂直地刺激皮肤,可通过调节伸长、更换Von Frey hairs纤毛机械刺激针调整刺激力大小,直到Von Frey hairs纤毛机械刺激针弯曲。当啮齿类动物得爪受到一个机械刺激,它们会缩回反射。该触觉测试可应用于大、小鼠的足底。
另外,可选配凿孔工作台,其网筛孔是利用激光切冲而成的方形孔,尺寸为5×5mm2 ,孔间距约为1mm,这对受试动物而言是一个舒适的环境,也便于操作人员观察动物的足底区域。该凿孔台经涂层处理,便于清洁且不易被腐蚀。
主要技术参数:
Von Frey hairs纤毛机械刺激针尼龙丝:no°20,校准偏差小于5%
Von Frey hairs test 刺激力:0.008-300g
可配合测试支架和大小鼠测试笼,对动物足底进行测试:
也可对人体或动物的其他部位的触觉反应,进行测试:
测痛实验大鼠固定器
可用于大鼠的面部、背部、腹部的刺痛实验;
可根据老鼠的体重订做合适的尺寸;
Touch Test
The Semmes-Weinstein monofilaments provide an approximate logarithmic scale of actual force, and a linear scale of perceived intensity. They have a long history of effective use in clinical settings, and can be used to diagnose pathologies of hyper- or hypo-aesthesia. Subsets within the set of 20 probes distinguish pathologies on different parts of the body (foot, hand, lip, cheek,etc.).
Semmes-Weinstein Von Frey Aesthesiometer for touch assessment
Features
Set of 20 monofilaments based on the Semmes-Weinstein monofilament set
Features retractable filaments to protect the filament
Allows the researcher to carry a few in a pocket
The Semmes-Weinstein monofilaments provide an approximate logarithmic scale of actual force, and a linear scale of perceived intensity. They have a long history of effective use in clinical settings, and can be used to diagnose pathologies of hyper- or hypo-aesthesia. Subsets within the set of 20 probes distinguish pathologies on different parts of the body (foot, hand, lip, cheek,etc.).
Operating Principle When the tip of a fiber of given length and diameter is pressed against the skin at right angles, the force of application increases as long as the researcher continues to advance the probe, until the fiber bends. After the fiber bends, continued advance creates more bend, but not more force of application. This makes it possible for the researcher using a hand-held probe to apply a reproducible force, within a wide tolerance, to the skin surface.
Pre-Clinical Use Rodents exhibit a paw withdrawal reflex when the paw is unexpectedly touched. The Touch Test? Sensory Evaluator can be used on the Plantar surfaces of the foot of a rat or mouse. The animal indicates sensation by pulling back its paw. Individual filaments available.