HIV type 1 Glycoprotein 160

Endoproteolytic processing of human immunodeficiency virus type 1 (HIV1) gp160 membrane glycoprotein precursor into gp120 and gp41 is necessary for formation of infectious HIV particles. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.