Anti-MTNR1A/MTR-1A/MEL-1A-R褪黑素受体1A/松果体素受体1A抗体

本公司提供科研MTNR1A/MTR-1A/MEL-1A-R褪黑素受体1A/松果体素受体1A抗体，抗体质量可靠，订购MTNR1A/MTR-1A/MEL-1A-R褪黑素受体1A/松果体素受体1A抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：褪黑素受体1A/松果体素受体1A抗体
英文名称：Anti-MTNR1A/MTR-1A/MEL-1A-R
货号：bs-0027R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 39kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, shp, cow, dog, pig, chk
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.Function : High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.Subcellular Location : Cell membrane; Multi-pass membrane protein.Tissue Specificity : Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus.Similarity : Belongs to the G-protein coupled receptor 1 family. 褪黑激素受体1A- 此抗体是MTR-1A特异性抗体，与MTR-1B无交叉反应。MEL-1A-R除分布在视网膜和下丘脑外，还广泛存在于多个组织中，也是有重着要生理活性的激素。 产品图片Antigen: bs-0027P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; TMB(C-0024) staining; Read the data in MicroplateReader by 450nm.