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LBP1/Upstream Binding Protein 1上游结合蛋白1抗体,抗体质量可靠,订购
LBP1/Upstream Binding Protein 1上游结合蛋白1抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
上游结合蛋白1抗体英文名称:
Anti-LBP1/Upstream Binding Protein 1货号:bs-6730R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 60kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, pig, cow, dog, hrs, chk
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.Function : UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells.Subunit : Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.Subcellular Location : Nucleus.Tissue Specificity : Expressed in adrenal tissue, JEG-3, NCI-H29, HepG2 and HeLa cell lines.Similarity : Belongs to the grh/CP2 family. CP2 subfamily.