Anti-phospho-HRH1(Ser398)磷酸化组胺受体H1抗体

本公司提供科研phospho-HRH1(Ser398)磷酸化组胺受体H1抗体，抗体质量可靠，订购phospho-HRH1(Ser398)磷酸化组胺受体H1抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：磷酸化组胺受体H1抗体
英文名称：Anti-phospho-HRH1(Ser398)
货号：bs-6665R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 54kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, hrs, cow, dog, Gpig
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].Function : In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.Subcellular Location : Cell membrane; Multi-pass membrane protein.Post-translational modifications : Potential sites of phosphorylation in the third cytoplasmic loop may play an important role in regulating signal transduction through the receptor molecule.Similarity : Belongs to the G-protein coupled receptor 1 family.