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Vinculin粘着斑蛋白抗体,抗体质量可靠,订购
Vinculin粘着斑蛋白抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
粘着斑蛋白抗体英文名称:
Anti-Vinculin货号:bs-6640R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 125kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, dog, cow, pig, hrs, chk, Rb
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.Subunit : Exhibits self-association properties. Interacts with NRAP and SORBS1 (By similarity). Interacts with TLN1. Interacts with SYNM. Interacts with CTNNB1 and this interaction is necessary for its localization to the cell-cell junctions and for its function in regulating cell surface expression of E-cadherin.Subcellular Location : Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side.Tissue Specificity : Metavinculin is muscle-specific.Similarity : Belongs to the vinculin/alpha-catenin family.