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ENO1+ENO2+ENO3神经元,肌肉特异性烯醇化酶抗体,抗体质量可靠,订购
ENO1+ENO2+ENO3神经元,肌肉特异性烯醇化酶抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
神经元,肌肉特异性烯醇化酶抗体英文名称:
Anti-ENO1+ENO2+ENO3货号:bs-6273R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 48kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011].