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GTPBP4/CRFGGTP结合蛋白4抗体(慢性肾功能衰竭蛋白),抗体质量可靠,订购
GTPBP4/CRFGGTP结合蛋白4抗体(慢性肾功能衰竭蛋白)请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
GTP结合蛋白4抗体(慢性肾功能衰竭蛋白)英文名称:
Anti-GTPBP4/CRFG货号:bs-6010R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 74kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [Entrez Gene]