Anti-phospho-LCK(Tyr394)磷酸化淋巴细胞特异性蛋白酪氨酸激酶抗体

本公司提供科研phospho-LCK(Tyr394)磷酸化淋巴细胞特异性蛋白酪氨酸激酶抗体，抗体质量可靠，订购phospho-LCK(Tyr394)磷酸化淋巴细胞特异性蛋白酪氨酸激酶抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：磷酸化淋巴细胞特异性蛋白酪氨酸激酶抗体
英文名称：Anti-phospho-LCK(Tyr394)
货号：bs-5406R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 56kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, chk, Rb
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].Subcellular Location : Cytoplasm. Cell membrane; Lipid-anchor; Cytoplasmic side.Tissue Specificity : Expressed specifically in lymphoid cells.Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. Contains 1 protein kinase domain. Contains 1 SH2 domain. Contains 1 SH3 domain.Lck淋巴细胞特异性蛋白酪氨酸激酶，是近年来发现的一种非受体型蛋白酪氨酸激酶，存在于T淋巴细胞及其它一些非T淋巴细胞内，参与细胞的信号转导过程，在多种生理及病理过程中发挥着重要作用。