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PMVK磷酸甲羟戊酸激酶抗体,抗体质量可靠,订购
PMVK磷酸甲羟戊酸激酶抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
磷酸甲羟戊酸激酶抗体英文名称:
Anti-PMVK货号:bs-5371R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 22kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.Subcellular Location : Peroxisome.Tissue Specificity : Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung.