Anti-P4HB蛋白二硫键异构酶P4HB抗体

本公司提供科研P4HB蛋白二硫键异构酶P4HB抗体，抗体质量可靠，订购P4HB蛋白二硫键异构酶P4HB抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：蛋白二硫键异构酶P4HB抗体
英文名称：Anti-P4HB
货号：bs-5090R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 57kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：P4HB, Prolyl 4 hydroxylase subunit beta, is a multifunctional and highly abundant enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds.Subcellular Location : Endoplasmic reticulum lumen. Melanosome. Cell membrane. Highly abundant. In some cell types, seems to be also secreted or associated with the plasma membrane, where it undergoes constant shedding and replacement from intracellular sources (Probable). Localizes near CD4-enriched regions on lymphoid cell surfaces. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.Similarity : Belongs to the protein disulfide isomerase family. Contains 2 thioredoxin domains.