Anti-Insig1胰岛素诱导基因1抗体

本公司提供科研Insig1胰岛素诱导基因1抗体，抗体质量可靠，订购Insig1胰岛素诱导基因1抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：胰岛素诱导基因1抗体
英文名称：Anti-Insig1
货号：bs-5074R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 30/50kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element binding protein (SREBP) mediated signaling pathway. Insig1 is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. Insig1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. It may also play a role in growth and differentiation of tissues involved in metabolic control, and may play a regulatory role during G0/G1 transition of cell growth.胰岛素诱导基因1在参与代谢控制的组织生长和分化中发挥作用，在细胞生长的G0/G1期的转变过程中发挥调节作用.