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Calponin 1/2/3钙结合蛋白Calponin抗体,抗体质量可靠,订购
Calponin 1/2/3钙结合蛋白Calponin抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
钙结合蛋白Calponin抗体英文名称:
Anti-Calponin 1/2/3货号:bs-4902R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 34kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, pig, hrs, cow, dog
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated myosin. Both properties are lost following phosphorylation (primarily at Serine 175) by protein kinase C or calmodulin-dependent protein kinase II. The three forms of Calponin, Calponin 1 (basic Calponin), Calponin 2 (neutral Calponin) and Calponin 3 (acidic Calponin) are found in smooth muscle tissue. Additionally, Calponin 2 is found in heart muscle tissue and Calponin 3 is found in the brain.Tissue Specificity : Smooth muscle, and tissues containing significant amounts of smooth muscle.