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GREB1乳腺癌雌激素调控蛋白GREB1抗体,抗体质量可靠,订购
GREB1乳腺癌雌激素调控蛋白GREB1抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
乳腺癌雌激素调控蛋白GREB1抗体英文名称:
Anti-GREB1货号:bs-3854R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 214kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, dog, pig, cow, Rb, chk
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:GREB1 is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. GREB1 is expressed in proliferating prostate tissue & prostate cancer and is thought to act as a regulator of hormone-dependent cancer growth in breast and prostate cancers. Its promoter contains putative androgen receptor response elements. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Function : May play a role in estrogen-stimulated cell proliferation. Acts as a regulator of hormone-dependent cancer growth in breast and prostate cancers.Subcellular Location : Membrane; Single-pass membrane protein (Potential).Tissue Specificity : Expressed in proliferating prostatic tissue and prostate cancer.Similarity : Belongs to the GREB1 family.GREB1是雌激素受体调节通路中早起反应基因,在乳腺癌、前列腺癌及前列腺增生中发挥着重要的调节作用。