Anti-phospho-VEGF receptor 2 (Tyr996)磷酸化血管内皮生长因子受体2抗体

本公司提供科研phospho-VEGF receptor 2 (Tyr996)磷酸化血管内皮生长因子受体2抗体，抗体质量可靠，订购phospho-VEGF receptor 2 (Tyr996)磷酸化血管内皮生长因子受体2抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：磷酸化血管内皮生长因子受体2抗体
英文名称：Anti-phospho-VEGF receptor 2 (Tyr996)
货号：bs-3470R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 26kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 and phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.