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Phospho-PSD93 (Tyr340)磷酸化突触后密度蛋白93抗体,抗体质量可靠,订购
Phospho-PSD93 (Tyr340)磷酸化突触后密度蛋白93抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
磷酸化突触后密度蛋白93抗体英文名称:
Anti-Phospho-PSD93 (Tyr340)货号:bs-3348R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 96kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, chk, dog, hrs
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.Subunit : Interacts through its PDZ domains with NETO1. Subcellular Location : Membrane; Lipid-anchor. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse.Similarity : Belongs to the MAGUK family. Contains 1 guanylate kinase-like domain. Contains 3 PDZ (DHR) domains. Contains 1 SH3 domain.