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Aurora A/ARK-1/AURKA有丝分裂激酶A抗体,抗体质量可靠,订购
Aurora A/ARK-1/AURKA有丝分裂激酶A抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
有丝分裂激酶A抗体英文名称:
Anti-Aurora A/ARK-1/AURKA货号:bs-2749R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 48kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, cow, Rb, hrs, pig
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.细胞的有丝分裂是生物体Z基本的生命活动过程,能将复制的基因组精确地分配到下一代子细胞中,在长期的生物进化过程中,生物体形成了一整套完善的监测机制以确保遗传物质精确地分配到子细胞中。Aurora激酶(极光激酶)是细胞有丝分裂调控网络中的一类重要的丝氨酸/苏氨酸激酶,Aurora酪氨酸激酶B也是丝氨酸/苏氨酸激酶家族成员之一,目前分为aurora A,B及C。