Anti-DGAT1/Diglyceride acyltransferase二脂酰甘油酰基转移酶抗体

本公司提供科研DGAT1/Diglyceride acyltransferase二脂酰甘油酰基转移酶抗体，抗体质量可靠，订购DGAT1/Diglyceride acyltransferase二脂酰甘油酰基转移酶抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：二脂酰甘油酰基转移酶抗体
英文名称：Anti-DGAT1/Diglyceride acyltransferase
货号：bs-2332R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 55kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, hrs, dog, pig
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. DGAT1 is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. DGAT1 is involved in fat absorption in the intestine and in basal level triglyceride synthesis in adipose tissue, where it is more highly expressed. Function : Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.Subunit : Homodimer or homotetramer (By similarity).Subcellular Location : Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity).Similarity : Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.