Anti-Claudin 11/OSP(Oligodendrocyte Marker)少突胶质细胞跨膜蛋白抗体

本公司提供科研Claudin 11/OSP(Oligodendrocyte Marker)少突胶质细胞跨膜蛋白抗体，抗体质量可靠，订购Claudin 11/OSP(Oligodendrocyte Marker)少突胶质细胞跨膜蛋白抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：少突胶质细胞跨膜蛋白抗体
英文名称：Anti-Claudin 11/OSP(Oligodendrocyte Marker)
货号：bs-2183R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 22kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, Gpig, pig, Rb, hrs, cow, chk, dog
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Oligodendrocyte Marker Oligodendrocyte specific protein (OSP)is the third most abundant component of central nervous system myelin. The claudin superfamily consists of many structurally related proteins. These proteins, which include claudin 1 through 18, are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that OSP/Claudin 11 determines the permeability between layers of myelin sheaths via focal adhesion. Its expression is highly regulated during development, suggesting that it may play an important role in the growth and differentiation of oligodendrocytes and other cells outside the CNS. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.Subunit : Interacts with tetraspanin-3/TSPAN3.Subcellular Location : Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.Similarity : Belongs to the claudin family.