本公司提供科研
RXR Alpha/RXRA/Retinoid X receptor核受体RXRα抗体,抗体质量可靠,订购
RXR Alpha/RXRA/Retinoid X receptor核受体RXRα抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
核受体RXRα抗体英文名称:
Anti-RXR Alpha/RXRA/Retinoid X receptor货号:bs-1379R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 51kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, rat, mo
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.