Anti-gamma tubulin(Centrosome Marker )微管蛋白γ抗体（Tubulin γ）

本公司提供科研gamma tubulin(Centrosome Marker )微管蛋白γ抗体（Tubulin γ），抗体质量可靠，订购gamma tubulin(Centrosome Marker )微管蛋白γ抗体（Tubulin γ）请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：微管蛋白γ抗体（Tubulin γ）
英文名称：Anti-gamma tubulin(Centrosome Marker )
货号：bs-1322R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 50kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, chk, Gpig, cow, hrs, dog, Rb
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Centrosome Marker Gamma tubulin, a member of the tubulin superfamily, is a ubiquitous and highly conserved protein within the microtubule organizing centre (MTOC). Gamma tubulin is not a component of microtubules, rather it functions as the microtubule nucleator at the MOTC, is responsible for binding microtubule minus ends and mediating the link between microtubles and the centrosome. By binding to the beta tubulin subunit of the tubulin molecule, it establishes the polarity of a microtubule leaving the alpha tubulin subunit exposed at the positive end. The abundance of Gamma tubulin is less than 1% of the level of either alpha or beta tubulin. It shares approximately 28-32% identity with alpha tubulin from various organisms and 32-36% identity with beta tubulins. The detection, localization and characterization of proteins involved in microtubule function is fundamental to the understanding of mitosis, meiosis and the microtubule cytoskeleton.Subcellular Location : Cytoplasm, cytoskeleton, centrosome.Similarity : Belongs to the tubulin family.结构蛋白（Structural Proteins） gamma tubulin 微管蛋白是存于ZX体的另一种微管蛋白, gamma微管蛋白对微管的形成具有重要作用。gamma微管蛋白通过与β-微管蛋白的相互作用帮助微管的成核反应(nucleation)。即在微管的组装中gamma微管蛋白先形成一个圆或形成钩环结构, γ微管蛋白的这种结构可指导微管蛋白二聚体结合上去并进行微管的组装。gamma微管蛋白在微管的组装中起关键作用。